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Buspirone (BUSPAR)
Visualize Pharmacology
Buspirone (Buspar) is a serotonin 5-HT1A partial agonist used for generalized anxiety disorder. It is generally nonsedating and does not produce benzodiazepine-type dependence.
Buspirone mechanism of action
Buspirone’s principal anxiolytic action involves serotonin 5-HT1A receptors. Its benefit develops gradually rather than immediately, so it is not an as-needed treatment for acute anxiety.
Buspirone metabolism and interactions
Buspirone is a CYP3A4 substrate. CYP3A4 inhibitors and grapefruit can increase exposure. The interaction avatar is a mnemonic for this metabolic pathway.
Buspirone visual mnemonics
Use the medication mascot, receptor ballicule, interaction avatar, and molecular structure to connect buspirone’s name with its pharmacology.
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