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CYP2B6

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“Tube Socks”

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3% of individuals are 2B6 ultrarapid metabolizers. 7% are poor metabolizers

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Conclusion: Fortunately, there are no strong inhibitors or inducers of 2B6. For psychiatrists, 2B6 is of minimal significance, unless methadone is being prescribed (see above). You will want to run an interaction check (e.g., ePocrates or Lexicomp) whenever a medication regimen includes a shredder, cancer medication, HIV medication, or systemic antifungal.

Cytochrome p450 2B6 inducer mnemonicsby Dr Jason Cafer MD's Psychopharmacology

There are no strong 2B6 inducers.

CYP2B6 inhibitors visual mnemonics by Dr Jason Cafer MD's Psychopharmacology

There are no strong 2B6 inhibitors.

CYP2B6 inducers carbamazepine tegretol phenytoin dilantin phenobarbital luminal rifampin rifadin efavirenz nevirapine ritonavir by Dr Jason Cafer MD's Psychopharmacology
BYP2B6 inhibitors mnemonics orphenadrine norflex clopidogrel plavix by Dr Jason Cafer MD's Psychopharmacology
CYP2B6 substrates mnemonics selegiline eldepryl emsam zoloft sertraline bupropion wellbutrin by Dr Jason Cafer MD's Psychopharmacology
CYP2B6 substrates mnemonics ketamine ketalar esketamine spravato methadone dolophine propofol diprivan by Dr Jason Cafer MD's Psychopharmacology
CYP2B6 substrates cyclophosphamide cytoxan efavirenz sustiva ifosfamide ifex nevirapine viramune by Dr Jason Cafer MD's Psychopharmacology
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