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COBENFY (xanomeline + trospium), related meds—and all things muscarinic—to understand and remember
Cobenfy, xanomeline + trospium, the next-generation antipsychotic is 9 out of 10 a big deal. Understand in context of all things muscarinic

Jason Cafer MD
Sep 30, 20247 min read


Donanemab (KISUNLA) FDA-approved for Alzheimer's: Should we recommend it?
Antibody vs N3pG Aβ is relatively safe but effect size in improved functioning may not be clinically significant, brain atrophy is a concern

Jason Cafer MD
Jul 9, 20248 min read


Donepezil (ARICEPT) mascot
Medical mnemonics for donepezil (Aricept) including drug-drug interactions

Jason Cafer MD
Aug 26, 20232 min read


Allopurinol for bipolar mania / The brain on uric acid
New medication mascot for allopurinol, which can be used off-label as adjunctive treatment of bipolar mania

Jason Cafer MD
Feb 26, 20233 min read


Eyeball lithium levels and suicide / Why not 150 mg?
Lower micro-lithium levels appear to be associated with suicide. Why not prescribe lithium 150 mg for prevention of suicide and Alzheimer's

Jason Cafer MD
Feb 12, 20233 min read


Alzheimer's antibody Lecanemab (LEQEMBI)
LEQEMBI (lecanemab) compared to ADUHELM (aducanumab) for mild Alzheimer's disease

Jason Cafer MD
Jan 8, 20232 min read
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