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Lithium Toxicity is Preventable and Avoidable - Memorize Lithium Interactions
Memorize the factors leading to lithium toxicity, focusing on interactions. PDF of visual mnemonics and 99 versions of this mnemonic song.

Jason Cafer MD
Jul 22, 20241 min read
372 views
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Arachidonic Acid and Bipolar Disorder
Arachidonic acid (AA), an omega-6 PUFA, may be deficient in bipolar disorder. Bipolar risk is strongly linked to AA-related genes. Lithium ↑

Jason Cafer MD
May 12, 20242 min read
142 views
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Interaction of the week: Lamotrigine (Lamictal) + Valproate (Depakote)
Lamotrigine + Valproate interaction Valproate (divalproex / valproic acid) doubles serum levels of lamotrigine by inHibiting UGT enzymes....

Jason Cafer MD
Aug 27, 20231 min read
807 views
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The one-page Psychopharmacology Algorithms sheet I refer to on a daily basis
One page PDF, evidence-based medicine reference for psychopharmacology

Jason Cafer MD
Mar 19, 20232 min read
3,920 views
1 comment


Allopurinol for bipolar mania / The brain on uric acid
New medication mascot for allopurinol, which can be used off-label as adjunctive treatment of bipolar mania

Jason Cafer MD
Feb 26, 20233 min read
596 views
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Eyeball lithium levels and suicide / Why not 150 mg?
Lower micro-lithium levels appear to be associated with suicide. Why not prescribe lithium 150 mg for prevention of suicide and Alzheimer's

Jason Cafer MD
Feb 12, 20233 min read
590 views
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Never accelerate lamotrigine titration (and know the UGT interactions)
This post was inspired by the Carlat Podcast: Psychopharm Commandment 4: Lamotrigine Rash. When is it advisable to accelerate the...

Jason Cafer MD
Feb 5, 20232 min read
923 views
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Virtual Darkness Therapy for Mania
100% blue-light-blocking glasses (amber-tinted) were found highly effective for treatment of acute mania, adjunctively to standard...

Jason Cafer MD
Aug 22, 20202 min read
276 views
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