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COBENFY (xanomeline + trospium), related meds—and all things muscarinic—to understand and remember
Cobenfy, xanomeline + trospium, the next-generation antipsychotic is 9 out of 10 a big deal. Understand in context of all things muscarinic

Jason Cafer MD
Sep 30, 20247 min read
3,444 views
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Clozapine: Mechanisms of its Unique Efficacy and Unusual Constellation of Side Effects
Clozapine's efficacy is from mechanisms other than D2 blocking, e.g., NMDA receptor agonism. The nororcloz metabolite causes salivation.

Jason Cafer MD
May 11, 20242 min read
872 views
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Guide to QT-prolonging medication
Among the commonly prescribed antipsychotics, 3 have moderate risk of QT prolongation: haloperidol, quetiapine, and ziprasidone (24 mascots)

Jason Cafer MD
May 9, 20243 min read
737 views
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Advantages and disadvantages of Risvan, the new LAI for schizophrenia
No oral overlap is needed.
No loading dose required.
Minimal pain and low incidence of injection site reactions.

Jason Cafer MD
Apr 14, 20242 min read
474 views
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Risperidone / Paliperidone LAI conversion tables, and why I'm favoring Uzedy
Equivalent Dose and Drug Conversions: How to convert between doses of risperidone, paliperidone, Uzedy, Perseris, Invega Sustenna, Trinza

Jason Cafer MD
Oct 18, 20232 min read
4,010 views
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Medication mascots and conversion tables for all of the risperidone, paliperidone, and aripiprazole LAIs
Aristada, Asimtufii, Consta, Hafyera, Initio, Maintena, Perseris, Rykindo, Sustenna, Trinza, Uzedy—which are which? Here are my...

Jason Cafer MD
Jul 22, 20231 min read
1,865 views
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Droperidol (INAPSINE)
We've added 2 more medications to the PDF version of Cafer's Psychopharmacology: Visualize to Memorize 270 Medication Mascots, so now...

Jason Cafer MD
Sep 15, 20211 min read
330 views
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