Dr Cafer interview on Precision Health & PGX Podcast

Check out the video version of this podcast for a sneak peak of Cafer's Psychopharmacology 2nd edition, in the works for 2025.

https://www.youtube.com/watch?v=DF-xCTTnIKs

Iconic Health Medication Iconographs

Medication mascots for remembering trade/generic name pairings

Quetiapine is effective for mania. "Sera, quit typing and go to sleep!"

Fluvoxamine is a fluffer inHibitor

Carbamazepine is a shredder inDucer

Anything that's an ax decreases levels of anything medication that's a tree

Carbamazepine decreases levels of CYP1A2 substrates

Hydrocarbons in cigarette smoke decrease levels of duloxetine (not applicable to nicotine vape, gum, or patch)

Fluvoxamine increases levels of lumateperone

Anything that's a pump increases levels of any medication that is a beach ball.

CYP2D6 inhibitors increase 2D6 prodrug substrates (bowling balls), will resultant decrease in efficacy

Inducers of CYP2D6 do not exist.

Effects of CYP2D6 metabolizer genotype on serum brexpiprazole levels.

CYP2D6 poor metabolizers will have diminished efficacy of bowling balls (2D6 prodrugs)

Anything that's a watering can will increase levels of any medication that's a flower.

Fluvoxamine increases levels of TCAs by inhibition of CYP2C19.

The well known ballicule visualization of Stahl's Essential Psychopharmacy, for comparison

Alternate visuals from Cafer's Psychopharmacology 2nd Edition (2025)

Neurotransmitters from Stahl's Essential Psychopharmacology, for comparison

Neurotransmitters are ballicules in Cafer's Psychopharmacology 2nd Edition (2025). The ring around epinephrine signifies poor penetrance across the blood-brain barrier.

"Anti-neurotransmitter" visuals from Cafer's Psychopharmacology 2nd Edition (2025)

How to bioengineer a psychotropic medication from "anti-neurotransmitters"

CaferMed ballicules include visuals for pharmacokinetic drug interactions. Also note that fluvoxamine is a sigma-1 agonist which may confer neuroprotection, anxiolytic effects, and amelioration of psychotic depression. Sertraline is the opposite as a sigma-1 inverse agonist which may have anti-cancer effects but there is theoretical concern for neurotoxicity.

Pharmacokinetic elements of ballicules

InHibitors increase levels of sensitive substrates for a particular enzyme.

InDucers decrease substrate levels

Overlapping elements between ballicules and interaction avatars. The hole in the top of the glass box signifies the possibility of some pharmacokinetic interaction(s) that are unlikely to be clinically relevant or that are beyond the scope of the visual mnemonic framework.

Cafer's Psychopharmacology: Memorize 270 Medication Mascots (formatted PDF)

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Cafer's Psychopharmacology: Memorize 270 Medication Mascots (paperback)

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