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Nitrous Oxide for Treatment-Resistant Depression, Potential Advantages Over (Es)ketamine
1-hr of inhaled nitrous oxide is efficacious for depression within 2 hr. NO2 is an NMDA receptor antagonist like (es)ketamine.

Jason Cafer MD
May 10, 20243 min read
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BupropiDex is not Auvelity
It's just the dex. This info is intended for prescribers. Auvelity (dextromethorphan hydrobromide + bupropion ER) was approved as a...

Jason Cafer MD
Mar 14, 20243 min read
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Oral zuranolone (ZURZUVAE) approved for postpartum depression
zuranolone (ZURZUVAE) compared to brexanolone (ZULRESSO) for treatment of postpartum depression, mnemonic mascots

Jason Cafer MD
Aug 7, 20233 min read
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Interaction of the week: Atomoxetine (Strattera) + Bupropion (Wellbutrin)
Atomoxetine (Strattera) + Bupropion (Wellbutrin) is a treacherous ADHD combo. I don't prescribe these two together, but it may be...

Jason Cafer MD
Jul 29, 20231 min read
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The one-page Psychopharmacology Algorithms sheet I refer to on a daily basis
One page PDF, evidence-based medicine reference for psychopharmacology

Jason Cafer MD
Mar 19, 20232 min read
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FDA approves Psilocybin for depression (is anticipated)
Information about psilocybin, which is anticipated to be approved for treatment-resistant depression.

Jason Cafer MD
Jan 29, 20233 min read
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Cilostazol (PLETAL) for depression
Cilostazol (PLETAL) Pronounced: sye LOE sta zol / PLAY tal FDA-approved for: Intermittent claudication Used off-label for: Depression...

Jason Cafer MD
Nov 15, 20212 min read
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