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Interaction of the week: Allergy to tramadol + Allergy to codeine
A patient with documented allergies to tramadol and codeine is likely a CYP2D6 poor metabolizer (10% of population). This one is not a...

Jason Cafer MD
Aug 18, 20235 min read


Omeprazole (Prilosec) mnemonics, interactions and risk of dementia
Medical mnemonics for omeprazole

Jason Cafer MD
Aug 12, 20233 min read


Interaction of the week: Olanzapine (Zyprexa) + Carbamazepine (Tegretol)
Pharmacokinetic Interaction Carbamazepine may decrease the serum concentration of olanzapine by about 50% (25%-71%) by inDuction of...

Jason Cafer MD
Aug 11, 20231 min read


Understanding Alpha-2 Agonists: mascots and ballicules for NE, clonidine, dexmedetomidine, etc.
Norepinephrine – endogenous neurotransmitter, α1 > α2 > β receptor agonist Clonidine – imidazoline > α2 receptor agonist Guanfacine –...

Jason Cafer MD
Aug 8, 202316 min read


Oral zuranolone (ZURZUVAE) approved for postpartum depression
zuranolone (ZURZUVAE) compared to brexanolone (ZULRESSO) for treatment of postpartum depression, mnemonic mascots

Jason Cafer MD
Aug 7, 20233 min read


Interaction of the week: Mirtazapine (Remeron) + Clonidine
Explanation of the interaction between mirtazapine (Remeron) and clonidine (Catapres)

Jason Cafer MD
Aug 4, 20232 min read


Interaction of the week: Atomoxetine (Strattera) + Bupropion (Wellbutrin)
Atomoxetine (Strattera) + Bupropion (Wellbutrin) is a treacherous ADHD combo. I don't prescribe these two together, but it may be...

Jason Cafer MD
Jul 29, 20231 min read


Medication mascots and conversion tables for all of the risperidone, paliperidone, and aripiprazole LAIs
Aristada, Asimtufii, Consta, Hafyera, Initio, Maintena, Perseris, Rykindo, Sustenna, Trinza, Uzedy—which are which? Here are my...

Jason Cafer MD
Jul 22, 20231 min read


Riluzole (RILUTEK) for OCD
Mnemonic phrase: “Riled tech (with) Real uzi” Pronunciation: RIL yoo zole / RIL yoo tek Interactions: CYP1A2 substrate (tree) Year...

Jason Cafer MD
Jun 11, 20233 min read


Brixadi vs Sublocade (buprenorphine SC LAIs) with mnemonics
Brixadi is the second (to Sublocade) long-acting injectable (LAI) of buprenorphine to be available in the US.

Jason Cafer MD
Jun 1, 20235 min read


Visual mnemonics for the CGRP-opposing migraine medications
New medication mascots for "zooms", "noob" and (ge)"pants" migraine medications for remembering trade/generic name pairings

Jason Cafer MD
Mar 22, 20232 min read


The one-page Psychopharmacology Algorithms sheet I refer to on a daily basis
One page PDF, evidence-based medicine reference for psychopharmacology

Jason Cafer MD
Mar 19, 20232 min read


Allopurinol for bipolar mania / The brain on uric acid
New medication mascot for allopurinol, which can be used off-label as adjunctive treatment of bipolar mania

Jason Cafer MD
Feb 26, 20233 min read


The Adderall Shortage: what to prescribe and how to convert doses
Contents: Bottom line: what to do Why the shortage and how long will it last? Comparing dextroamphetamine to levoamphetamine Why is pure...

Jason Cafer MD
Feb 19, 20233 min read


Eyeball lithium levels and suicide / Why not 150 mg?
Lower micro-lithium levels appear to be associated with suicide. Why not prescribe lithium 150 mg for prevention of suicide and Alzheimer's

Jason Cafer MD
Feb 12, 20233 min read


Never accelerate lamotrigine titration (and know the UGT interactions)
This post was inspired by the Carlat Podcast: Psychopharm Commandment 4: Lamotrigine Rash. When is it advisable to accelerate the...

Jason Cafer MD
Feb 5, 20232 min read
"New" drug approval: Rykindo
The latest psychiatric medication to receive FDA approval is Rykindo, a long-acting injectible (LAI) of risperidone administered every 2...

Jason Cafer MD
Jan 30, 20231 min read


FDA approves Psilocybin for depression (is anticipated)
Information about psilocybin, which is anticipated to be approved for treatment-resistant depression.

Jason Cafer MD
Jan 29, 20233 min read


Tirzepatide (MOUNJARO) - potential for unprecedented weight loss
Today the PDF version of Cafer's Psychopharmacology was updated with four new medication mascots, including Tirzepatide (MOUNJARO)....

Jason Cafer MD
Jan 22, 20232 min read


Meds used for ECT: Succinylcholine (ANECTINE)
Mnemonic: “A nectarine Sucks in a coal line" Pronunciation: suks in il KOE leen / an EK teen Class: Depolarizing neuromuscular blocking...

Jason Cafer MD
Jan 17, 20235 min read
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